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Moderna Begins Patient Dosing in Phase 1/2 Study of Seasonal Flu mRNA Vaccine Candidate; Shares Fall

Biotechnology company Moderna (MRNA) revealed that patient dosing has begun in its Phase 1/2 study of quadrivalent seasonal influenza mRNA vaccine candidate mRNA-1010. Its shares closed nearly 5% lower on Wednesday and fell another 2.7% in pre-market trading on Thursday.

The company develops vaccines and therapeutics for the treatment of cardiovascular diseases, rare diseases, immuno-oncology and infectious diseases.

The study, which will enroll 180 healthy adults, will check the immunogenicity, reactogenicity and safety of the candidate. (See Moderna stock chart on TipRanks)

mRNA-1010 is the company’s first seasonal influenza vaccine candidate that has achieved the World Health Organization’s clinic and targets lineages for the prevention of influenza, including influenza B Yamagata, Victoria, seasonal influenza A H1N1 and H3N2.

The CEO of Moderna, Stéphane Bancel, said, “We expect that our seasonal influenza vaccine candidates will be an important component of our future combination respiratory vaccines. Our vision is to develop an mRNA combination vaccine so that people can get one shot each fall for high efficacy protection against the most problematic respiratory viruses.”

On July 7, Piper Sandler analyst Edward Tenthoff maintained a Buy rating on the stock with a price target of $246 (10.9% upside potential). In a research note to investors, the analyst said, “Moderna could revolutionize the seasonal flu vaccine market where today’s protection rates are only 40%-60%.”

Overall, the stock has a Moderate Buy consensus rating based on 7 Buys, 4 Holds and 2 Sells. The average Moderna price target of $192.8 implies 13.1% downside potential. The company’s shares have gained 260.3% over the past year.

According to TipRanks’ Smart Score rating system, Moderna scores a “Perfect 10,” suggesting that the stock is likely to outperform market averages.

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Richika Biyani
Based out of India, Richika is a seasoned writer with more than 15 years of experience in news and report writing. She also writes financial blogs. In the past, Richika has covered stocks trading on the NYSE, NASDAQ, and TSX. She is a postgraduate in finance and holds a Bachelor's degree in finance and accounting. Richika started her career by writing short news stories and she now writes stock analysis pieces for TipRanks. She has also held leadership positions in her previous organizations. Richika believes that a good writer has the superpower to easily explain even the most complex ideas and concepts in the simplest of words. She thinks reading helps a great deal in achieving this and so she reads anything and everything that she can find. Apart from being an avid reader, Richika enjoys cooking, swimming, and playing tennis. Follow me on LinkedIn